GATE Biotechnology syllabus online tests books

GATE Biotechnology paper overview

Biotechnology is relatively new branch of Engineering. It is perceived to be growing branch on Engineering in future.Candidates with BTECH or BE in Biotechnology can apply for this paper. I have written separate article on eligibility criteria and other details of GATE Exams (post link).

You can read that post for details on eligibility criteria. You can also post your questions related to the exam there as well.In this article I will cover below points related to GATE Biotechnology paper

  1. Paper statistics
  2. Free Online tests
  3. Recommended Books
  4. Detailed Syllabus
  5. Free Android App

GATE Biotechnology paper statistics

Below statistics will help you get important insight about the exams.So lets see some interesting facts about this paper

  1. Number of candidates registered for the exam – 11,000(approx)
  2. Number of candidates appeared for the exam – 9,000(approx)
  3. Number of qualified candidates – 1936
  4. Percentage of candidates qualified – 21.5% (approx)
  5. Maximum marks out of 100 – 64.33
  6. Minimum marks out of 100 – 18
  7. Average marks – 31.35
  8. Standard Deviation – 6.88

The selection rate in Biotechnology paper is higher than that of many other papers. This is good news for candidates.However the maximum marks is one of the lowest.This means it is tough to get good marks but it is easy to pass the exams.

The average marks is around 31 marks.This means if you score more than 50 marks then you will get good marks.While planning and preparing for the exams you should keep this fact in mind.There is no point planning to score 100 marks. If you plan to study everything then quality will degrade.

You can plan the section you should focus on and get you marks close to 70 then it is fine. The quality of preparation should be good.You should be able to answer all questions or most questions from that section.

GATE Biotechnology Online tests

Online tests are best way to see how prepared you are before real exams.It is a kind of litmus test.But to be really useful online tests should have good questions.Questions should be aimed to exams.So we have created GATE Biotechnology online test series.All the questions in this online test series are carefully selected with upcoming GATE exams in mind.

You can try the online test using below links.Note the tests are completely free.

The online tests have all the features of real exam.It has negative marking.It has time limit.So you will feel that you are attempting real exams.Above tests have questions from previous year GATE exams and important questions for current year GATE exams. For best results you should attempt all the test papers.

GATE Biotechnology Recommended Book

Your text books can be used as study material.But some students want dedicated book for exams.Dedicated books help them by providing topics in concise form.Out of the books available in market you can follow below books.I have mentioned few options that will help you make decision.

I have mentioned the books in order of preference. You can read the details about the books and then decide which one you want to opt for.

Book 1

The book is divided into three sections General Aptitude, Engineering Mathematics and Biotechnology. The biotechnology section is divided into 10 sections. Each section has theory part as well as questions. The chapters has good number of solved questions.

These questions are based on previous year question pattern.You may have similar type of questions in coming exams as well.The book also contains last eight years’ (2010-2017) solved papers of original online GATE Biotechnology to give the aspirants an insight into the trends of questions asked in GATE Examination.

The book also has practice test set.The logic along with problem make this book an excellent companion for exam.The book has close to 1,000 pages and has good rating as well. You can buy the book from below link in discounted price.

Click to buy Biotechnology GATE 2018

Book 2

This book also covers theory as well as problems.The book has around 1,000 pages. The book is good one. The unique feature of the book is 24*7 support via mobile app and online portal.This feature is missing in first book.It also has solved questions from previous year GATE exams.

There is not much difference between first and second book. You can select the first one or the second one.There is not much difference. You can buy second book from below link with discount. I kept this book at second slot due to price difference.

Click to buy Gate Guide Biotechnology 2018

Book 3

This book is third choice.This is not dedicated GATE book.This book covers competitive exams like CSIR- NET, SET, GATE, JNU, AIIMS, JAM, ICAR, ICMA etc. All thesr exams are basically objective type and basic concepts of life science subjects as mentioned above. This book includes the basic concepts of all the important topics of biotechnology entrance and for Phd entrance.

Also this book contains miscellaneous questions collection for student practice or for revision of basic concepts. This book is helpful for the student of different stream of life science who wants to qualify JNU, CSIR NET or other competitive examination. This book is also helpful for those students who wants a brief notes on different topics of biotechnology for preparation of university examination.

Click to buy Biotechnology for CSIR – NET, SET, GATE, JNU, AIIMS, JAM

GATE Biotechnology syllabus

Below is syllabus of GATE Biotechnology.The syllabus is taken from official website of GATE exams(link). So it is updated and authentic syllabus.You should copy the syllabus and then mark the topics.For preparation cover topic by topic.This way you will not skip between the topics.You will know topics you have covered and topics left.The online test also helps you find out topics important for exams as well.

Section 1: Engineering Mathematics

Linear Algebra: Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors. Calculus: Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier Series. Differential Equations: Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE-Laplace, heat and wave equations.

Probability and Statistics: Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis. Numerical Methods: Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations.

Section 2: General Biotechnology


Biomolecules-structure and functions; Biological membranes, structure, action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain; Bioenergetics


Viruses- structure and classification; Microbial classification and diversity(bacterial, algal and fungal); Methods in microbiology; Microbial growth and nutrition; Aerobic and anaerobic respiration; Nitrogen fixation; Microbial diseases and host-pathogen interaction

Cell Biology

Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction

Molecular Biology and Genetics

Molecular structure of genes and chromosomes; Mutations and mutagenesis; Nucleic acid replication, transcription, translation and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics (plasmids, transformation, transduction, conjugation); Horizontal gene transfer and Transposable elements; RNA interference; DNA damage and repair; Chromosomal variation; Molecular basis of genetic diseases

Analytical Techniques

Principles of microscopy-light, electron, fluorescent and confocal; Centrifugation- high speed and ultra; Principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS,NMR; Principles of chromatography- ion exchange, gel filtration, hydrophobic interaction, affinity, GC,HPLC, FPLC; Electrophoresis; Microarray


History of Immunology; Innate, humoral and cell mediated immunity; Antigen; Antibody structure and function; Molecular basis of antibody diversity; Synthesis of antibody and secretion; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organ; B and T cells and macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction.


Major bioinformatic resources and search tools; Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny);Data mining and analytical tools for genomic and proteomic studies; Molecular dynamics and simulations (basic concepts including force fields, protein-protein, protein-nucleic acid, protein-ligand interaction)

Section 3: Recombinant DNA Technology

Restriction and modification enzymes; Vectors; plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; mammalian and plant expression vectors; cDNA and genomic DNA library; Gene isolation, cloning and expression ; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy

Section 4: Plant and Animal Biotechnology

Totipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and Cell suspension culture system: methodology, kinetics of growth and, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root culture; transgenic plants;

Plant products of industrial importance Animal cell culture; media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro-carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals

Section 5: Bioprocess Engineering and Process Biotechnology

Chemical engineering principles applied to biological system, Principle of reactor design, ideal and non-ideal multiphase bioreactors, mass and heat transfer; Rheology of fermentation fluids, Aeration and agitation; Media formulation and optimization; Kinetics of microbial growth, substrate utilization and product formation;

Sterilization of air and media; Batch, fed-batch and continuous processes; Various types of microbial and enzyme reactors; Instrumentation control and optimization; Unit operations in solid-liquid separation and liquid-liquid extraction; Process scale-up, economics and feasibility analysis Engineering principle of bioprocessing- Upstream production and downstream; Bioprocess design and development from lab to industrial scale;

Microbial, animal and plant cell culture platforms; Production of biomass and primary/secondary metabolites; Biofuels, Bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins; Industrial application of chromatographic and membrane based bioseparation methods; Immobilization of biocatalysts (enzymes and cells) for bioconversion processes; Bioremediation-Aerobic and anaerobic processes for stabilization of solid / liquid wastes


You should focus on topics mentioned above while preparing.You can safely ignore other topics.Above resources if used properly are enough to help you get good marks in GATE Biotechnology paper.Also if you want any help regarding GATE biotechnology paper you can post your question.I would try to revert.

You can also use below Android App. This App has GATE Biotechnology questions with answers. So you can prepare for the exams for free.The Android App is completely free.

GATE Exams Android Mobile App

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